August 2025

FDA approves updated Covid vaccines, including mRNA shots from Pfizer, Moderna

August 28, 2025 / News update / InnovateMed Author / covid vaccine

by Max Bayer The FDA on Wednesday approved updated formulas of the Covid-19 vaccines ahead of the fall respiratory season, though the labels are more limited than in years past. Vaccines were approved for Pfizer, Moderna and Novavax for all adults 65 and older and people younger than 65 who are at higher risk of […]

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Metformin May Shield Against Dementia in Overweight/Obesity

August 28, 2025 / Research update / InnovateMed Author / metformin, obesity

TOPLINE: During a 10-year follow-up, metformin use was associated with significantly lower risks for both dementia and all-cause mortality in patients with overweight or obesity. METHODOLOGY: Metformin, the most widely prescribed glucose-lowering treatment, is linked to a reduced risk for dementia in patients with diabetes; however, its effect on the incidence of dementia among individuals

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Transplanted Islet Cells Survive Without Immune Suppression

August 28, 2025 / Research update / InnovateMed Author / immune suppression, transplanted islet

For the first time, researchers have transplanted gene-edited donor islet cells that secrete insulin in a person with type 1 diabetes (T1D) without the use of immunosuppression. Twelve-week results from the phase 1, single-participant study were published online on August 4, 2025, as a Brief Report in The New England Journal of Medicine. Six-month data were presented on

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patient education – Diabetes in the Heat: Overlooked Risks That Could Cost Lives

August 28, 2025 / Clinical Practice, Patient education / InnovateMed Author / diabetes, heat waves

Current high temperatures can put significant stress on people with chronic illnesses, including those with diabetes, and may also affect diagnostics and therapy. Several experts explain what people with diabetes and their clinicians should pay attention to during extreme heat. High-Risk Groups “The body’s own temperature regulation is often impaired in people with diabetes. The

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Gut-Lung Axis: Implications and Clinical Relevance for Pulmonology

August 28, 2025 / Research update / InnovateMed Author / gut lung axis

Emerging insights into the gut-lung axis continue to open new possibilities for managing chronic respiratory diseases, from cystic fibrosis (CF) in the youngest patients to chronic obstructive pulmonary disease (COPD) in older adults. Despite growing evidence linking gut health to respiratory disease pathogenesis, these findings are not yet ready for routine clinical application. Still, they underscore the

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First enzyme-targeting drug reverses damage in metabolic fatty liver disease

August 28, 2025 / Research update / InnovateMed Author / metabolic fatty liver disease

by University of California – San Diego edited by Gaby Clark, reviewed by Robert Egan Credit: CC0 Public Domain Researchers at the University of California San Diego School of Medicine have identified a new investigational drug that shows promise in treating metabolic dysfunction-associated steatohepatitis (MASH), a serious form of fatty liver disease linked to obesity and type 2

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New treatment with designer proteins could disrupt cycle of addiction without stifling natural pleasure

August 28, 2025 / Research update / InnovateMed Author / protein

by Miles Martin, University of California – San Diego edited by Lisa Lock, reviewed by Andrew Zinin Chimeric ion channels that are activated by cocaine. Credit: Nature (2025). DOI: 10.1038/s41586-025-09427-8 A new biochemical approach to combat addiction, developed by researchers at the University of California San Diego and the National Institute on Drug Abuse (NIDA), has shown promising results

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Researchers study natural curb on cancer as potential therapy

August 28, 2025 / Research update / InnovateMed Author / cancer

by Mary Martialay, Purdue University edited by Lisa Lock, reviewed by Andrew Zinin G4 conformation–based protein recognition for G4 epigenetic transcription control. Credit: Science (2025). DOI: 10.1126/science.adr1752 Could a natural check on cancer be used to stop the disease? It’s possible, but to leverage a system that nature designed, we must first understand it. Researchers led by a team at

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Insomnia patients report better sleep when taking cannabis-based medical products

August 28, 2025 / Research update / InnovateMed Author / insomnia

by Public Library of Science edited by Stephanie Baum, reviewed by Robert Egan Credit: Unsplash/CC0 Public Domain Insomnia patients taking cannabis-based medical products reported better quality sleep after up to 18 months of treatment, according to a study published in PLOS Mental Health by Arushika Aggarwal from Imperial College London, U.K., and colleagues. About one out of every three people has some

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Targeting viral envelope glycans offers promising path toward world’s first broad-spectrum antiviral

August 28, 2025 / Research update / InnovateMed Author / broad spectrum antiviral

by CUNY Advanced Science Research Center edited by Gaby Clark, reviewed by Robert Egan Ebola virus particles (red) on a larger cell. Credit: NIAID Researchers at the Nanoscience Initiative at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have made a breakthrough in the fight against viral diseases. Their study, published in the

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