August 25, 2025

Survey reveals people are not aware knee and groin pain can be signs of hip problems

by Ohio State University Medical Center edited by Sadie Harley, reviewed by Robert Egan   Matthew Beal, M.D., an orthopedic surgeon with The Ohio State University Wexner Medical Center, tests the patient’s hip mobility. Credit: The Ohio State University Wexner Medical Center Having a hard time bending over to put your shoes on? Experiencing pain in the knees, […]

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Annual mental health screenings recommended for U.S. youth

by Dennis Thompson edited by Sadie Harley, reviewed by Andrew Zinin Pediatricians should screen children annually for mental or developmental issues, the American Academy of Pediatrics (AAP) recommends in a new clinical report. The recommendation comes in response to a mental, emotional and behavioral health crisis that’s been brewing among America’s youth, the AAP says. Up to

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FDA clears OTC glucose monitoring system for weight management

by Stephanie Brown edited by Sadie Harley, reviewed by Andrew Zinin The U.S. Food and Drug Administration has cleared the Signos Glucose Monitoring System, an over-the-counter glucose monitoring system for weight management. Signos integrates the Stelo by Dexcom glucose biosensor with an artificial intelligence-driven platform to show how food, activity, stress, sleep, and timing affect the body in real

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Human hippocampal neurogenesis shows unique gene expression patterns compared to other mammals

by Ingrid Fadelli, Phys.org edited by Gaby Clark, reviewed by Robert Egan   Cross-species analysis of immature neurons in the hippocampus. Leveraging machine-learning-augmented scRNA-seq analysis, the team identified imGCs with transcriptome-wide immature neuronal characteristics in different mammals. They then performed cross-species comparisons of imGCs and mature granule cells (mGCs) from humans, monkeys, pigs and mice. Credits: Yi Zhou,

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Universal plug-and-play CAR-T cell therapy could transform cancer immunotherapy

by University of Chicago Medical Center edited by Lisa Lock, reviewed by Robert Egan Design of the GA1CAR. Credit: Science Advances (2025). DOI: 10.1126/sciadv.adv4937 Researchers at the University of Chicago have developed a “universal” chimeric antigen receptor (CAR) platform that offers enhanced safety, adaptability, and the potential to overcome long-standing barriers in cancer immunotherapy. Promising initial testing results, published in Science Advances, suggest

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Cutting alcohol use linked to reduced hospital visits for mental health treatment among primary care patients

by Research Society on Alcohol edited by Lisa Lock, reviewed by Andrew Zinin   Credit: Unsplash/CC0 Public Domain Changes in unhealthy alcohol use over time can be measured by a simple questionnaire at annual primary care visits. A study published in Alcohol, Clinical and Experimental Research found that in a primary care population that is regularly screened for alcohol use, decreased alcohol

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Alcohol use disorder is profoundly undertreated during and after pregnancy, leaving parents and infants at risk

by Research Society on Alcohol edited by Lisa Lock, reviewed by Andrew Zinin Credit: Unsplash/CC0 Public Domain In recent years, binge drinking and alcohol use disorder (AUD) rates during pregnancy have increased significantly in the United States, eclipsing even opioids. Evidence-based treatments for AUD include medications and counseling. Still, these are underused, including during pregnancy when both the

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Genetic study suggests ways to catch blood cancer earlier – genetics

New understanding of how mutations interact could pave way for early detection, prevention strategies by Julia Evangelou Strait•August 21, 2025 DrawImpacts A new WashU Medicine study shows that acquired mutations in blood stem cells — whether arising from smoking, exposure to toxins or even normal aging — interact with mutations passed down by parents in important

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Can Gastroesophageal Reflux Disease Increase Colonic Neoplasia Risk?

TOPLINE: An analysis of older adults revealed that subtypes of gastroesophageal reflux disease (GERD) such as erosive esophagitis, nonerosive reflux disease, and Barrett esophagus were associated with an increased risk for colonic neoplasia, with the risk more pronounced for colon polyps than for colorectal cancer. METHODOLOGY: In symptomatic GERD, patients are commonly treated with long-term

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