August 5, 2025

Preclinical study finds modified protein can aid heart attack recovery

by Cedars-Sinai Medical Center edited by Lisa Lock, reviewed by Robert Egan Credit: Pixabay/CC0 Public Domain A preclinical study led by the Smidt Heart Institute at Cedars-Sinai challenges the assumption that blocking the NCX1 protein, which regulates calcium levels in cells, is more effective than maintaining its activity during a heart attack to limit damage. The findings, published in the Proceedings […]

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Beyond classic stress signaling: How mitochondrial stress softens the cell nucleus and alters cellular identity

by Anna Euteneuer, University of Cologne edited by Sadie Harley, reviewed by Robert Egan The image shows the cross-section mutant brown adipose tissue section with enlarged lipid droplets (yellow) and nucleus (blue) being impinged by multiple mitochondria (red). Credit: Harshita Kaul/Universität zu Köln Mitochondria are specialized structures within cells that are primarily responsible for energy production but that

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A saliva-based test for breast cancer might be near

by Ernie Mundell edited by Gaby Clark, reviewed by Andrew Zinin In a small new study, a handheld saliva-sampling device successfully detected breast cancer 100% of the time, researchers said. The study only involved 29 saliva samples, and more research is needed. However, the results remain “very exciting because this device could improve access to breast cancer screening and

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Inflammation linked to frailty, social deprivation and heart disease risk in women

by King’s College London edited by Gaby Clark, reviewed by Robert Egan Overview of the study design. Credit: Communications Medicine (2025). DOI: 10.1038/s43856-025-01012-4 A new study led by researchers at King’s College London, in collaboration with the University of Nottingham, suggests that chronic inflammation may link frailty, social disadvantage and increased cardiovascular disease (CVD) risk. The findings, published in Communications Medicine, could help

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Bone-building discovery could transform osteoporosis treatment

By Paul McClure August 03, 2025 Facebook Twitter Flipboard LinkedIn Reddit Email Scientists have discovered a way to significantly improve bone strength Depositphotos View 3 Images View gallery – 3 images A newly discovered receptor switch that boosts bone growth could transform how we treat osteoporosis, by stimulating the body’s own bone-building machinery using a targeted

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