July 25, 2025

What Are Nootropics? Mechanisms, Efficacy, and Safety of Cognitive Enhancers

By Pooja Toshniwal PahariaReviewed by Benedette Cuffari, M.Sc. Introduction Mechanisms of action Categories of nootropics Prescription nootropics Natural nootropics Synthetic/OTC nootropics Evidence of efficacy Safety, tolerance, and side effects Ethical and social considerations Conclusions References Further reading From herbal extracts to synthetic stimulants, nootropics promise sharper thinking, but at what cost? Explore how these brain-boosting agents work, […]

What Are Nootropics? Mechanisms, Efficacy, and Safety of Cognitive Enhancers Read More »

Creatine may enhance neuroprotection through energy pathways

  Download PDF Copy By Dr. Liji Thomas, MDReviewed by Lauren HardakerJul 25 2025 Scientists reveal how creatine could do more than build muscle, fueling brain resilience, enhancing mood, and supporting cognitive performance through exercise-driven biochemical pathways.  Study: Creatine supplementation and muscle-brain axis: a new possible mechanism? Image credit: Sonis Photography/Shutterstock.com Creatine supplementation is widely acknowledged for boosting muscular mass and

Creatine may enhance neuroprotection through energy pathways Read More »

Heavy smoking linked to atrophy in Alzheimer’s brain regions

By Dr. Priyom Bose, Ph.D.Reviewed by Lauren HardakerJul 25 2025 New MRI research reveals that heavy smoking can shrink key brain regions tied to memory and cognition, and excess weight might intensify the damage, raising fresh questions about dementia prevention. Study: Smoking predicts brain atrophy in 10,134 healthy individuals and is potentially influenced by body mass index. Image

Heavy smoking linked to atrophy in Alzheimer’s brain regions Read More »

Which signalling pathways in the cell lead to possible therapies for Parkinson’s disease

New triggers for mitophagy – a self-cleaning process in cells – discovered Peer-Reviewed Publication University of Vienna image: Fig. 1: Sascha Martens (left) and Elias Adriaenssens (right). view moreCredit: Max Perutz Labs Autophagy is essentially the ‘rubbish collection’ of our cells. If there are problems in this process, which is so important for our health, diseases

Which signalling pathways in the cell lead to possible therapies for Parkinson’s disease Read More »

Chronic kidney disease may be tied to higher risk for tooth loss

by Elana Gotkine edited by Stephanie Baum, reviewed by Andrew Zinin Chronic kidney disease (CKD) appears to be associated with a higher risk of tooth loss, with a higher prevalence of CKD seen among individuals with fewer than 20 teeth, according to a study published online July 20 in Renal Failure. Na-Yeong Kim, from the Chonnam National University School of

Chronic kidney disease may be tied to higher risk for tooth loss Read More »

Previously undetectable biomarkers in gut microbiome may predict ‘invisible’ chronic fatigue syndrome, long COVID

by Jackson Laboratory edited by Sadie Harley, reviewed by Andrew Zinin Credit: CC0 Public Domain Millions suffering from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a debilitating condition often overlooked due to the lack of diagnostic tools, may be closer to personalized care, according to new research that shows how the disease disrupts interactions between the microbiome, immune system, and

Previously undetectable biomarkers in gut microbiome may predict ‘invisible’ chronic fatigue syndrome, long COVID Read More »

‘Powerful new approach’: New drug combination strategy shows promise against hard-to-treat cancers

by Virginia Tech edited by Sadie Harley, reviewed by Andrew Zinin Credit: Ivan Samkov from Pexels A potential target for experimental drugs that block PRMT5—a naturally occurring enzyme some tumors rely more on for survival—has been identified by researchers with the Fralin Biomedical Research Institute’s Cancer Research Center in Washington, D.C. In a study published in Cancer Research, Assistant

‘Powerful new approach’: New drug combination strategy shows promise against hard-to-treat cancers Read More »

Male birth control pill clears initial safety hurdle

by Justin Jackson, Phys.org edited by Sadie Harley, reviewed by Andrew Zinin Credit: Pixabay/CC0 Public Domain YourChoice Therapeutics, working with Quotient Sciences and Incyte, reports that single oral doses of the investigational non‑hormonal male contraceptive YCT‑529 up to 180 mg produced no clinically relevant safety issues in 16 healthy men. Unintended pregnancies account for roughly half of conceptions

Male birth control pill clears initial safety hurdle Read More »

Measles cases just reached 30-year high in the US: How bad is California surge?

by Hannah Poukish and Fernanda Galan edited by Sadie Harley, reviewed by Andrew Zinin Credit: Unsplash/CC0 Public Domain Measles cases in California and the United States are climbing to levels the country hasn’t seen in years. So far in 2025, the disease has infected 1,319 people nationwide, leading to 29 outbreaks and 165 hospitalizations, according to the

Measles cases just reached 30-year high in the US: How bad is California surge? Read More »

Study finds key gene loss may trigger premature aging in the brain

by Nara Institute of Science and Technology edited by Sadie Harley, reviewed by Andrew Zinin  A decline in the expression of the epigenetic regulator Setd8 in neural stem cells (NSCs) during early adulthood leads to chromatin condensation and reduced gene expression, suppressing NSC proliferation and contributing to premature brain aging. This illustration depicts the transition of NSCs from

Study finds key gene loss may trigger premature aging in the brain Read More »

Scroll to Top