July 9, 2025

Implantable device could save diabetes patients from dangerously low blood sugar

July 9, 2025 / Research update / InnovateMed Author / low blood sugar

by Massachusetts Institute of Technology edited by Sadie Harley, reviewed by Robert Egan A new implantable device carries a reservoir of glucagon that can be stored under the skin and could save diabetes patients from dangerously low blood sugar. Credit: MIT For people with type 1 diabetes, developing hypoglycemia, or low blood sugar, is an ever-present threat. […]

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Understanding childhood maltreatment and its effect on biological aging

July 9, 2025 / Clinical Practice / InnovateMed Author / biological aging, child maltreatment

by the University of Fukui edited by Gaby Clark, reviewed by Robert Egan The plots shown above depict a marked link between a child’s biological age, as determined through DNA methylation age (mAge), and their visual attention for eyes. These factors are also linked to higher scores in the Strength and Difficulties Questionnaire (SDQ)—an indicator of

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Injectable HIV Prevention Drug Gets FDA Nod – pharmaceutical

July 9, 2025 / Clinical Practice / InnovateMed Author / HIV prevention drug

Individuals at risk for sexually acquired HIV have a new injectable option for preexposure prophylaxis (PrEP) with the US Food and Drug Administration’s (FDA’s) approval of lenacapavir, according to a press release from manufacturer, Gilead. Lenacapavir, marketed as Yeztugo, is the first twice-yearly injectable to be indicated for PrEP for adults and adolescents weighing at least 35

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FDA approves new dosing of Lilly’s Alzheimer’s drug to lower brain swelling risks

July 9, 2025 / Clinical Practice / InnovateMed Author / alzheimer, brain swelling risk

FDA approves new dosing of Lilly’s Alzheimer’s drug to lower brain swelling risks Ryan Cross Senior Science Correspondent Eli Lilly’s new Alzheimer’s drug is off to a slow start, but the Indianapolis drugmaker hopes that an update to the treatment’s prescription label may help build confidence among doctors and patients who have been hesitant to

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Gut Microbiome Changes in Chronic Pain — Test and Treat?

July 9, 2025 / Research update / InnovateMed Author / chronic pain, gut microbiome

A new study adds to what has been emerging in the literature — namely that there appear to be gut microbiome “signatures” for various pain conditions — suggesting that microbiome-based diagnostics and therapeutics may one day be routine for a broad range of pain conditions. “There is now a whole list of pain conditions that appear to

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Oral Semaglutide: By Year’s End, a GLP-1 Weight-Loss Pill?

July 9, 2025 / Research update / InnovateMed Author / oral semaglutide, weight loss pill

With a GLP-1 in pill form for weight loss expected to be FDA-approved by year’s end, obesity medicine physicians said they are gearing up for higher demand and already answering questions about the anticipated new option. Predictions are mixed about how many people may dump the shots in favor of the pill, and some physicians

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Study finds 9% of young US employees use alcohol, drugs at work

July 9, 2025 / Research update / InnovateMed Author / alcohol use, drug use

by Emily Caldwell, The Ohio State University edited by Lisa Lock, reviewed by Andrew Zinin Predicted Prevalence of Past-Month Substance Use in the Workplace among US Workforce Aged 30–35 by Occupation, National Longitudinal Survey of Youth 1997. Credit: American Journal of Industrial Medicine (2025). DOI: 10.1002/ajim.23737 Almost 1 in 10 workers in their 30s uses alcohol, marijuana or hard

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‘Dimmer switch’ drug candidates offer hope for safer nerve pain and ischemic disease treatments

July 9, 2025 / Neurology, Research update / InnovateMed Author / ischemic disease treatment, nerve pain

by Monash University edited by Sadie Harley, reviewed by Robert Egan Cryo-EM structure of the human adenosine A1 receptor (A1R, white) in complex with the orthosteric agonist adenosine (magenta) and the allosteric modulator MIPS521 (cyan). Credit: Dr. Anh T.N. Nguyen, Monash University Scientists have discovered novel drug candidates which could ultimately lead to new effective treatments for conditions

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AI–based test detects early signs of osteoporosis from X-ray images

July 9, 2025 / Research update / InnovateMed Author / osteoporosis, x ray

by Wiley edited by Sadie Harley, reviewed by Robert Egan Credit: Pixabay/CC0 Public Domain Investigators have developed an artificial intelligence-assisted diagnostic system that can estimate bone mineral density in both the lumbar spine and the femur of the upper leg, based on X-ray images. The advance is described in a study published in the Journal of Orthopaedic

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New artificial intelligence–based test detects early signs of osteoporosis from X-ray images