July 7, 2025

Diabetes, Weight-Loss Drug Tied to Decreased Dementia Risk in T2D

TOPLINE: Semaglutide was associated with a 20%-46% reduced risk for Alzheimer’s disease (AD)-related dementia in patients with type 2 diabetes (T2D) compared with other antidiabetic medications, with a particularly strong protective effect against vascular dementia, new research showed. METHODOLOGY: Researchers examined electronic health records (EHRs) of more than 1.7 million US adults with T2D with […]

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Transabdominal Ultrasound May Help Monitor Cystic Pancreatic Lesion

TOPLINE: Transabdominal ultrasound (TAUS) demonstrated an 85.7% detection rate for cystic pancreatic lesions, which was also noted with endoscopic US (EUS), with BMI and lesion size significantly affecting the detection. METHODOLOGY: Researchers conducted a retrospective analysis including 105 adult patients (median age, 69 years; 62.9% women) with cystic pancreatic lesions who underwent both EUS and

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Promising Weight-Loss Compound Targets Energy Expenditure – obesity

A new weight-loss compound targeting energy expenditure rather than appetite suppression showed early efficacy in a first-in-human study. The compound, SANA (MVD1; Eolo Pharma), activates creatine-dependent thermogenesis, a novel approach to obesity and metabolic disease compared to appetite suppression, explained Eolo Pharma CEO María Pía Garat. “To our knowledge, SANA is the only small molecule

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Long-Acting Antibiotics Match Standard-of-Care Antibiotics in Serious Bacterial Infections

TOPLINE: In a large cohort, long-acting lipoglycopeptides (laLGPs) demonstrated comparable effectiveness to standard-of-care antibiotics for step-down treatment of serious Gram-positive bacterial infections in both individuals who used drugs and those who did not. METHODOLOGY: Standard antibiotic therapy for serious bacterial infections can be challenging due to stigma and logistical barriers associated with prolonged treatment. LaLGPs

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Landmark study reveals cell-level brain changes tied to PTSD

By Pranjal Malewar July 06, 2025 Facebook Twitter Flipboard LinkedIn Reddit The findings paint a detailed picture of how trauma leaves lasting marks on the brain—right down to the cell level. Depositphotos View 1 Images Post-traumatic Stress Disorder (PTSD) isn’t caused by just one faulty switch in the brain; it’s more like a tangled orchestra of

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Neem – Evidence-Based Health Benefits

By Hugo Francisco de SouzaReviewed by Benedette Cuffari, M.Sc. Introduction What is neem? Botanical profile Antimicrobial activity Antiviral effects Oral health applications Anti-inflammatory and immunomodulatory effects Dermatological applications Metabolic and chronic disease management Cancer and chemoprevention Safety, toxicity, and limitations Conclusion References Further reading Explore how centuries-old neem remedies are being validated by modern science, as researchers

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Chaotic and deeply frightening’: Once a global gold standard, US government health guidance is falling apart

by Corinne Purtill edited by Sadie Harley, reviewed by Andrew Zinin   Credit: Pixabay/CC0 Public Domain Weeks after President Donald Trump took office, multiple government webpages referencing gender and sexual orientation abruptly disappeared from the internet. Many returned after a February court order. But they came with an unusual addition: a disclaimer from the Department of Health

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How AI is helping researchers to demystify gut bacteria

by University of Tokyo edited by Stephanie Baum, reviewed by Andrew Zinin   VBayesMM uses paired microbiome-metabolite data, with microbial species as input variables and metabolite abundances as target variables. Credit: Briefings In Bioinformatics (2025). DOI: 10.1093/bib/bbaf30 Gut bacteria are known to be a key factor in many health-related concerns. However, the number and variety of them is vast, as

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Digital Twins: Medicine’s New Crystal Ball?

Digital twins are rapidly emerging as powerful tools in personalized medicine and beyond. In healthcare, they serve as virtual representations of a patient’s body, body parts, specific organs, and systems, such as the circulatory and nervous systems. Functional modeling of the state and behavior of the body or its components has the potential to provide information

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Natural compound mimics exercise’s anti-aging benefits – no gym needed

By Bronwyn Thompson July 04, 2025 Facebook Twitter Flipboard LinkedIn Reddit Scientists are a step closer to bottling the anti-aging benefits of exercise Depositphotos View 1 Images Harnessing the power of a metabolite produced in the kidneys and absorbed from certain foods can mimic the health benefits delivered by exercise, regulating inflammation and promoting an array

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