June 2025

Crohn’s disease investigational treatment shows potential for achieving remission

June 30, 2025 / Research update / InnovateMed Author / Crohn's disease

by Cedars-Sinai Medical Center edited by Lisa Lock, reviewed by Robert Egan High magnification micrograph of Crohn’s disease. Biopsy of esophagus. H&E stain. Credit: Nephron/Wikipedia Cedars-Sinai investigators have developed an investigational therapy that brought a significant number of patients with moderate to severe Crohn’s disease into remission, according to a new study published in The Lancet Gastroenterology & Hepatology. The […]

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A potential replacement for bone marrow sampling: New blood test may detect leukemia risk

June 30, 2025 / Research update / InnovateMed Author / leukemia

by Weizmann Institute of Science edited by Gaby Clark, reviewed by Robert Egan Mapping cHSPCs. Credit: Nature Medicine (2025). DOI: 10.1038/s41591-025-03716-5 What if a blood test could reveal the pace of our aging—and the diseases that may lie ahead? The labs of Profs. Liran Shlush and Amos Tanay at the Weizmann Institute of Science have been conducting in-depth studies

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New ‘smart capsule’ tracks health of the GI tract

June 30, 2025 / Research update / InnovateMed Author / GI tract

by California Institute of Technology edited by Gaby Clark, reviewed by Robert Egan PillTrek, a capsule electrochemical platform for continuous, multiplexed GI fluid analysis. Credit: Nature Electronics (2025). DOI: 10.1038/s41928-025-01407-0 Scientists are increasingly finding that the gastrointestinal (GI) tract plays a vital role in our overall health. While its main functions center around digestion, the GI tract is also

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AI tool detects 9 types of dementia from a single brain scan

June 30, 2025 / Research update / InnovateMed Author / dementia

by Mayo Clinic edited by Alexander Pol Dr. David Jones reviews brain scans on a computer at Mayo Clinic. Credit: Mayo Clinic Mayo Clinic researchers have developed a new artificial intelligence (AI) tool that helps clinicians identify brain activity patterns linked to nine types of dementia, including Alzheimer’s disease, using a single, widely available scan—a transformative

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People with severe diabetes cured in small stem cell trial

June 30, 2025 / Research update / InnovateMed Author / diabetes

by Craig Beall, The Conversation edited by Owen Ferguson, reviewed by Andrew Zinin Credit: Pixabay/CC0 Public Domain The cure for diabetes is a life free from daily insulin injections. Based on that criterion, ten out of 12 people (83%) in a new clinical trial were cured of their diabetes one year after receiving an advanced stem cell therapy. This study

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Scientists create functional 3D-printed human islets for type 1 diabetes treatment

June 30, 2025 / Research update / InnovateMed Author / type 1 diabetes

by European Society for Organ Transplantation edited by Gaby Clark, reviewed by Robert Egan Visualized using double immunostaining. Colors: red = glucagon antibody, blue = insulin antibody. Generated in Laboratory of nervous system development, FSBI Human Morphology SRI RAMS, Moscow. Credit: Afferent. This file is licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license. A team of international scientists

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Managing Weight in Older Adults Isn’t About Weight at All

June 30, 2025 / Patient education / InnovateMed Author / weight

While weight loss is often the goal of weight management, weight management in older adults should go beyond weight loss to focus on functional health outcomes, comorbidity improvements, and harm reduction. Beverly Tchang, MDWeight management in older adults requires greater mindfulness and clinical nuance than in younger populations, owing to the increased risk of potential

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Kombucha boosts obesity-fighting gut microbes – no diet required

June 30, 2025 / Patient education / InnovateMed Author / obesity

By Bronwyn Thompson June 21, 2025 Facebook Twitter Flipboard LinkedIn Reddit Just 200 mL a day transformed study participants’ microbiome Depositphotos View 1 Images A small daily dose of kombucha made from black tea has been shown to meaningfully reshape the gut microbiome in adults – particularly those with obesity – without any dietary changes. And,

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Novel PDE10A Inhibitor for Acute Schizophrenia Safe, Effective in Large Phase 2 Trial

June 30, 2025 / Research update, Uncategorized / InnovateMed Author / acute schizophrenia

LOS ANGELES — The novel phosphodiesterase 10A (PDE10A) inhibitor known as CPL’36 (Celon Pharma) is effective and generally safe in acute exacerbations of schizophrenia, new research suggested. In a phase 2 trial of 189 patients with acute schizophrenia, compared with the placebo group, the groups receiving CPL’36 20 or 40 mg once daily both met

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Weekly Pill Platform Succeeds in Schizophrenia, With Much Wider Promise

June 30, 2025 / Research update / InnovateMed Author / schizophrenia

A novel once-weekly capsule loaded with the antipsychotic risperidone, LYN-005, provided similar bioavailability and symptom control as daily doses of the drug in a phase 3 trial of patients with schizophrenia or schizoaffective disorder. The study was stopped early for success after an interim analysis showed all pharmacokinetic values met primary endpoint criteria. Weekly LYN-005

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