prostate cancer

Scans that make prostate cancer cells ‘glow’ can eliminate the need for invasive biopsies

The state of the art imaging test uses a molecule that binds to prostate cancer cells, causing them to “light up in a remarkable way”—appearing as bright spots in the scanning image. The process could safely halve the number of men who need to undergo a biopsy for suspected prostate cancer following inconclusive results from […]

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Hormone therapy may not benefit most men receiving radiotherapy after prostate surgery, study finds

by University of California, Los Angeles edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Marta Branco from Pexels A new study led by UCLA Health Jonsson Comprehensive Cancer Center investigators suggests that adding hormone therapy to postoperative radiotherapy may provide little survival benefit for most men with prostate cancer,

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A potential immunotherapy strategy for early-stage prostate cancer

by Jessica Saenz, Mayo Clinic edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Cell Reports Medicine (2026). DOI: 10.1016/j.xcrm.2026.102638 Immunotherapy has been generally ineffective for prostate cancer because the tumors are considered immunologically “cold,” meaning they do not attract enough immune cells to mount a strong attack. Hormone therapy commonly used

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A landmark ‘evolutionary double-bind’ strategy to overcome treatment resistance in prostate cancer

by Trinity College Dublin edited by Lisa Lock, reviewed by Alexander Pol  Editors’ notes  The GIST Add as preferred source Evolutionary double-bind therapy uses two therapies that explicitly target populations with different modes of therapy resistance. Credit: International Journal of Radiation Oncology*Biology*Physics (2026). DOI: 10.1016/j.ijrobp.2025.09.034 Many patients with metastatic cancers receive therapy that is initially highly effective, often resulting in

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New characteristics of aggressive prostate cancer identified

by Norwegian University of Science and Technology edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source This is what a frozen section of the prostate looks like. The researchers drilled small holes to extract tissue samples from areas where the gland contained cancer. It is precisely these tissue samples that were

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New study unlocks important information about how to treat recurring prostate cancer

by National Comprehensive Cancer Network edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: CC0 Public Domain New research appearing in the Journal of the National Comprehensive Cancer Network found that incorporating information from prostate-specific membrane antigen (PSMA) PET/CT scans may be able to predict progression-free survival (PFS) and guide treatment

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Half of all men over 60 have prostate cancer – an AI diagnostic tool could identify which need followup

Not all cases of prostate cancer need followup and treatment, but determining which are serious and which are benign has been challenging. Peer-Reviewed Publication Norwegian University of Science and Technology image: Prostate cancer is the most common form of cancer among men in Western countries. The disease is naturally linked to aging. Professor Tone Frost

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Randomized trial finds drug therapy reduces hot flashes during prostate cancer treatment

by Alliance for Clinical Trials in Oncology edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: oscar Williams from Pexels A national clinical trial led by the Alliance for Clinical Trials in Oncology has found that oxybutynin, a drug often used to treat overactive bladder symptoms, reduces hot flashes

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Predicting prostate cancer recurrence through power of AI

edited by Sadie Harley, reviewed by Andrew Zinin  Editors’ notes  The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain To help meet the potentially complex needs of patients after prostate cancer treatment and offer the precision and care necessary in the follow-up journey, Mayo Clinic’s Department of Radiation Oncology developed the PSA Control Tower. This is

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New model improves prediction of prostate cancer death risk

by American College of Physicians edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source Credit: Pixabay/CC0 Public Domain A new long-term prediction tool estimates the risk of dying from prostate cancer, offering a more accurate way to interpret prostate-specific antigen (PSA) test results compared to existing models. The tool, tested on

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