parkinson

by Autonomous University of Barcelona edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source In green, mouse dopaminergic neurons (substantia nigra). In magenta, microglia. In blue, cell nuclei. Credit: Inc-UAB By analyzing tissue from patients with Parkinson’s disease, and animal and cellular models of the disease, a research team from the […]

Universitat Autònoma de Barcelona (UAB)Feb 2 2026 By analyzing tissue from patients with Parkinson’s disease, and animal and cellular models of the disease, a research team from the Institut de Neurociències of the UAB has shown that the main immune cells of the brain become reactive and overexpress certain receptors that promote the elimination of dopaminergic

Peer-Reviewed Publication University College London New research reveals how Parkinson’s spreads from the gut to the brain, with the help of immune cells – offering a new potential therapeutic strategy – in a study in mice led by scientists at the UK Dementia Research Institute at UCL (University College London). Scientists have long theorised that

by Case Western Reserve University edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes  The GIST Add as preferred source ClpP modulates αSyn tetramer and aggregates. Credit: Molecular Neurodegeneration (2025). DOI: 10.1186/s13024-025-00918-w About 1 million Americans suffer from Parkinson’s disease, with around 90,000 new cases diagnosed each year, according to the Parkinson’s Foundation. The chronic, degenerative brain disorder destroys

by Iqra Bano edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes The image illustrates two advanced neuromodulation techniques used in PD treatment: A Deep Brain Stimulation (DBS) and B Focused Ultrasound (FUS). Credit: 3 Biotech (2026). DOI: 10.1007/s13205-025-04681-z Parkinson’s disease is no longer viewed as a faraway neurological ailment buried in textbooks. More than 10 million people

by Freda Kreier, Yale School of Medicine edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Preventing cell loss. Top: Dopamine cells (green) in the substantia nigra of healthy mice. Middle: Dopamine cells degenerate in mice exposed to misfolded α-synuclein. Bottom: In mice lacking mGluR4 and NPDC1, dopamine cells are preserved after exposure to misfolded α-synuclein. Credit:

by NYU Langone Health edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Credit: Unsplash/CC0 Public Domain The brain-chemical surge that comes with running may bolster coordination and speed in the old and young alike, a new study of middle-aged mice shows. Such physical activity may help restore ease of movement and agility, which often decline as

by Weill Cornell Medical College edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Glycogen synthase is expressed in dopaminergic axon terminals, enabling local glycogen storage. Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2523019122 Dopamine neurons in a part of the brain called the midbrain may, with aging, be increasingly susceptible to a vicious spiral of

by Murdoch University edited by Lisa Lock, reviewed by Andrew Zinin  Editors’ notes Credit: Pixabay/CC0 Public Domain An international study has found that wearable technology could help detect Parkinson’s disease (PD) up to nine years before clinical diagnosis simply by monitoring how people turn when they walk. The collaborative research, involving five institutions, including the University Hospital of