heart attack

PCSK9 inhibitor lowers risk of first heart attack and stroke in high-risk adults

by Mass General Brigham edited by Andrew Zinin  Editors’ notes Credit: Pixabay/CC0 Public Domain Researchers from Mass General Brigham have unveiled the results of a large clinical trial that found that adding the drug evolocumab to patients’ treatment significantly reduced the risk of major adverse cardiovascular events in those who are at high risk. Results were presented […]

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Drug-delivery patch could help to heal the heart following a heart attack

by Massachusetts Institute of Technology edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes The programmable drug-delivery patch. Credit: MIT MIT engineers have developed a flexible drug-delivery patch that can be placed on the heart after a heart attack to help promote healing and regeneration of cardiac tissue. The new patch is designed to carry several different

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Mapping the heart: How cells coordinate repair after heart attack

by Julius Maximilian University of Würzburg edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Spatiotemporal niches in cardiac wound healing. Credit: Nature Cardiovascular Research (2025). DOI: 10.1038/s44161-025-00739-6 Over the course of evolution, the human heart has largely lost its ability to regenerate. Our distant ancestors were not afflicted by heart attacks—a condition that emerged primarily with modern lifestyles

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Specific human gene can help the heart repair itself from heart attack or heart failure

by The Mount Sinai Hospital edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes From left to right – the cell in the initial frame is from a 55-year-old donor heart. The next image shows the cell rounding up after receiving Cyclin A2 and the cell division takes place shortly after. The third image represents the same

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Repurposing an arthritis drug could significantly improve recovery from heart attack

by Baker Heart & Diabetes Institute edited by Sadie Harley, reviewed by Robert Egan  Editors’ notes Graphical abstract. Credit: Cardiovascular Research (2025). DOI: 10.1093/cvr/cvaf165 Australian researchers have discovered that an anti-inflammatory drug already being used to treat rheumatoid arthritis could dramatically improve recovery from heart attacks. The work is published in the journal Cardiovascular Research. Even though most patients will survive

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Over 99% have a risk factor before heart attack, stroke or heart failure, large-scale study finds

by Northwestern University edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Credit: Pixabay/CC0 Public Domain More than 99% of people who went on to suffer a heart attack, stroke or heart failure already had at least one risk factor above optimal level beforehand, reports a large-scale study led by Northwestern Medicine and Yonsei University in South

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Heart attacks may be linked to bacterial infections, study finds

Bacterial infections may sometimes trigger heart attacks, a new study says. Image credit: Viaframe/Getty Images In 2022, about 19.8 million people globally died from heart disease, with about 85% of these deaths attributed to stroke and heart attack. Previous research has linked bacterial infections as a risk factor for heart disease. Past studies have also

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Mayo Clinic study reveals hidden causes of heart attacks in younger adults, especially women

Peer-Reviewed Publication Mayo Clinic ROCHESTER, Minn. — A new Mayo Clinic study finds that many heart attacks in people under 65 — especially women — are caused by factors other than clogged arteries, challenging long-standing assumptions about how heart attacks occur in younger populations. Study findings published in the Journal of the American College of Cardiology examined over 15 years of data

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Variations in glucose levels may indicate severity of heart attack damage

by Luciana Constantino, FAPESP edited by Stephanie Baum, reviewed by Robert Egan Credit: Pixabay/CC0 Public Domain According to research conducted by Brazilian scientists, high glucose levels may serve as a biomarker indicating a worse outcome in patients who have experienced their first acute myocardial infarction. The study demonstrated that glycemic variability, particularly glycemic delta, is associated with the

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Gene therapy restores functionality in non-human primates after heart attacks

New approach uses bacterial genes to restore both strength and rhythm of damaged hearts Peer-Reviewed Publication Duke University Biomedical engineers at Duke University have successfully conducted experiments to treat damage caused by heart attacks in non-human primates using gene therapy for the first time. More than 800,000 Americans suffer a heart attack every year. Even

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