cancer

Childhood cancer catalog opens door to pediatric immunotherapy

by Rob Clancy, Hudson Institute of Medical Research edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Credit: iScience (2025). DOI: 10.1016/j.isci.2025.113887 A unique facility in Melbourne containing hundreds of childhood cancer tissue samples has produced a first-of-its-kind catalog of pediatric cancers to help identify how the immune system can target each one. Pediatric cancer is the leading cause […]

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High risk of metastatic recurrence found among young cancer patients

by UC Davis edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Credit: Unsplash/CC0 Public Domain A new study of adolescents and young adults (AYAs) with seven common cancers reveals that nearly one in ten patients diagnosed with non-metastatic disease later develop metastatic recurrence—a condition associated with significantly worse survival outcomes. Metastasis is when cancer cells spread

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Two common $1.50 medications eliminate cancer-causing ‘forever chemicals’ from the body

READ MORE: Experts warn 100million Americans tap water contains PFAS By LUKE ANDREWS, US SENIOR HEALTH REPORTER Published: 10:48 EST, 6 November 2025 | Updated: 11:28 EST, 6 November 2025 e-mail View comments Cancer-causing forever chemicals building up in the body could be eliminated using two common medications that are readily available, scientists say. In a small study, scientists in Sweden tracked 10

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Smart exercise planning could boost recovery for people with cancer

by Edith Cowan University edited by Lisa Lock, reviewed by Robert Egan  Editors’ notes Credit: Unsplash/CC0 Public Domain The periodization of exercise training could give people undergoing cancer treatment and those in recovery a tailored pathway to support strength and resilience during the challenging journey of cancer care and rehabilitation. By strategically varying exercise mode, intensity, and volume

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How bacteria in tumors drive treatment resistance in cancer

by University of Texas M. D. Anderson Cancer Center edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Graphical abstract. Credit: Cancer Cell (2025). DOI: 10.1016/j.ccell.2025.09.010 Researchers from The University of Texas MD Anderson Cancer Center have discovered a previously unknown mechanism that explains how bacteria can drive treatment resistance in patients with oral and colorectal cancer. The study

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Experimental drug findings pave way for clinical trial to target cancer’s elusive growth switch

by The Francis Crick Institute edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes (A) Chemical structure of VVD ligands used in the manuscript. (B) Global proteomics selectivity of VVD-484, VVD-849, VVD-579, and VVD-844. Cells were treated with 10 µM of VVD-484, 2 µM of VVD-849 or VVD-579, or 1 µM of VVD-844, which is ~25-fold over

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Engineered CAR-NK cells could evade immune rejection and target cancer more effectively

by Massachusetts Institute of Technology edited by Stephanie Baum, reviewed by Robert Egan  Editors’ notes A new study identifies genetic modifications that make “natural killer” more effective at destroying cancer cells. Credit: NIAID One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar

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Alzheimer’s protein holds clues for fighting cancer

by Hayley Kamin, Medical University of South Carolina edited by Gaby Clark, reviewed by Robert Egan  Editors’ notes Credit: Medical University of South Carolina At first glance, Alzheimer’s disease and cancer have little in common. One erodes memory, while the other consumes the body. Yet researchers at MUSC Hollings Cancer Center have discovered an unexpected link connecting the

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Microbial allies: Bacteria help fight against cancer

by MRC Laboratory of Medical Sciences edited by Sadie Harley, reviewed by Robert Egan Graphical abstract. Credit: Cell Systems (2025). DOI: 10.1016/j.cels.2025.101397 An international team of scientists led by researchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College London and the University of Cologne have discovered that microbes associated with tumors produce a molecule that can control cancer

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Researchers uncover how COVID-19 may linger in cancer patients and affect treatment outcomes

by Ezra Xiong, University of Minnesota Medical School edited by Stephanie Baum, reviewed by Andrew Zinin Credit: iScience (2025). DOI: 10.1016/j.isci.2025.113438 New research from the University of Minnesota Medical School is providing important insights into how COVID-19 persists in cancer patients even long after testing positive. The findings were recently published in iScience. During the peak of COVID-19 in 2020, there was concern

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