Microdosing weight loss drugs?

A stock image of needles lined up in rows against a pink background

Adobe

Telehealth companies Noom, Found, and Hims & Hers have all launched programs to prescribe “microdosed” GLP-1s in the last three months, following in the steps of many smaller direct-to-consumer brands. They claim that compounded GLP-1s in small doses can reduce diabetes risk, lower inflammatory markers, and lower the risk of cognitive decline. But doctors and researchers say there’s no robust clinical evidence that these drugs are effective at very small doses, and the drugs aren’t proven to help patients with many of those symptoms.

It’s the latest move for telehealth companies that have been tweaking their formulations in order to continue selling compounded versions of GLP-1s after regulators decided there was no longer a shortage. Read more from STAT’s Katie Palmer on how companies are rolling out these programs, what experts think about the approach, and which celebrities have signed on to endorse it.


another big number

5,000

That’s the number of steps per day that could slow cognitive decline for people who are showing signs of Alzheimer’s, according to a study published yesterday in Nature Medicine. Researchers followed nearly 300 older adults with no cognitive impairment at the start of the study. Particularly among those with high levels of beta-amyloid (an early sign of the disease), low or moderate exercise levels seemed to slow cognitive decline. But that didn’t happen by slowing the buildup of beta-amyloid, as one might expect. Read more from STAT’s Jonathan Wosen on how exercise interacted with Alzheimer’s risk, and why some experts say interpreting the results can be tricky.

doctors

Medicare cuts pay for surgeries

In a blow to specialists, Medicare on Friday made good on its earlier proposal to cut payments for surgeries, outpatient procedures, and other services it believes can be done more efficiently, Tara Bannow reports.

The policy is both controversial and easy to miss, due to its technical nature, but Tara knows her stuff.

The policy involves a so-called efficiency adjustment, which assumes that advances in technology and standardized workflows reduce the time and expense of performing certain procedures. Medicare will cut pay rates 2.5% for those services starting Jan. 1.

Meanwhile, payments for time-based services that primary care doctors typically provide, such as office visits or behavioral health therapy, will not be cut. Telehealth and certain maternity services will also be unaffected.

Read more.

UnitedHealth Group pays its own physician practices much more than it pays competing practices

By Tara Bannow

Nov. 3, 2025

Hospitals and Insurance Reporter

UnitedHealth Group pays its own physician practices much more than it pays competing practices, a new study finds, reinforcing STAT’s own analysis on the subject and presenting fresh evidence that the conglomerate may be skirting a rule designed to curb health insurer profits.

UnitedHealth’s insurance arm, UnitedHealthcare, pays practices under its UnitedHealth-owned Optum umbrella 17% more on average for common services than it pays non-Optum practices in the same region, according to the study, published today in Health Affairs. In areas where its insurance arm has a large market share, it pays Optum practices 61% more.

from Politico:


DOC PAY —
 Physicians are scrambling to dissect the implications of a 2,300-page rule the Centers for Medicare and Medicaid Services released on Halloween night, which sets how Medicare will pay doctors.

Finalized Friday, the rule spells varied fates for doctors across disciplines. For example, allergists netted a 7 percent increase, but neurosurgeons will take a 5 percent cut. General practitioners — a focus of Health Secretary Robert F. Kennedy Jr.’s Make America Healthy Again agenda to combat chronic disease — will get a 3 percent bump in pay.

Doctors have good reasons to celebrate: CMS skipped its annual cut to Medicare reimbursements, offering a reprieve in 2026. While it’s not a permanent fix, it spares doctors another year of payment reductions. The rule also streamlines and expands telehealth, lifting visit-frequency limits for certain virtual services.

But the rule breaks with the American Medical Association, whose advisory committee has for decades recommended Medicare payments. That committee has long been criticized for favoring specialties over primary care. CMS called the group out for what it said were “overinflated” valuations.

The rule docks pay for most procedures by 2.5 percent, undercutting the AMA recommendations, arguing the treatments have become more efficient over time. But the rule goes several steps further, suggesting alternatives to the AMA in making these determinations.

CMS also declined to use a key AMA survey to calculate practice expenses, citing “low response rates” and other errors. The AMA has stood by the accuracy of its data.

CMS said it hopes to use hospital data instead. Their new calculation recognizes higher costs for providers not part of larger health facilities at the expense of many specialists associated with hospitals.

“This rule will make it harder for independent practices to remain viable parts of our health system,” AMA President Bobby Mukkamala said in a Monday news release.

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