February 27, 2026

A simple energy molecule gives female mice a memory boost

February 27, 2026 / Research update / InnovateMed Author / memory boost

by Paul Arnold, Medical Xpress edited by Lisa Lock, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Acetate facilitates long-term memory. Credit: Science Signaling (2026). DOI: 10.1126/scisignal.aec0496 A team of scientists from the U.S. has discovered that acetate, a simple molecule involved in how our bodies create energy, can significantly increase long-term memory in female mice. […]

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Potential treatment target in fatty liver disease identified

February 27, 2026 / Research update / InnovateMed Author / liver disease

by Petra Olsson, Lund University edited by Gaby Clark, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source (A) The overall study design. (B) Alluvial diagram of patient composition of groupings across liver histological features. (C) Relationship between clinical test results and stages of liver histological features. Node size was determined by –log10(p value) in

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Major study finds strong link between cannabis, anxiety and depression

February 27, 2026 / Research update / InnovateMed Author / cannabis

by McMaster University edited by Gaby Clark, reviewed by Alexander Pol Editors’ notes The GIST Add as preferred source Credit: Unsplash/CC0 Public Domain An analysis of 35,000 Canadians shows that rising cannabis use and worsening mental-health symptoms are increasingly appearing together, with the connection between the two strengthening over time. The study, led by McMaster University and published in The Canadian

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Paradigm shift in immune checkpoint biology

February 27, 2026 / Research update / InnovateMed Author / Paradigm shift

by Sungkyunkwan University edited by Sadie Harley, reviewed by Alexander Pol Editors’ notes The GIST Add as preferred source A research team led by Professor Ki-Young Lee at the College of Medicine, Sungkyunkwan University, has uncovered a previously unrecognized tumor-intrinsic role of the immune checkpoint molecule PD-L1, providing new mechanistic insight into lung cancer progression. The study was published online

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Quantitative imaging framework detects emerging form of dementia, limbic-predominant age-related

February 27, 2026 / Research update / InnovateMed Author / dementia

by Society of Nuclear Medicine and Molecular Imaging edited by Gaby Clark, reviewed by Alexander Pol Editors’ notes The GIST Add as preferred source Visual Abstract. Comparison of FDG PET 3D-SSP z score maps and transaxial slices of the temporal lobe, along with corresponding MRI images, among individuals suspected of having Alzheimer’s disease (AD), LATE, and mixed LATE and

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Starving cancer: The effects of nutrient deprivation on synovial sarcoma

February 27, 2026 / Research update / InnovateMed Author / Synovial sarcoma

by Osaka Metropolitan University edited by Sadie Harley, reviewed by Alexander Pol Editors’ notes The GIST Add as preferred source An in vivo experiment with model mice showed that the V9302 inhibitor can block glutamine uptake and cancer growth. Credit: Osaka Metropolitan University Synovial sarcoma is an aggressive malignant tumor that primarily affects the limbs of teenagers and

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Oral semaglutide found to lower risk of heart failure events in people with type 2 diabetes

February 27, 2026 / Research update / InnovateMed Author / type 2 diabetes

by Angela Yeager, Oregon Health & Science University edited by Lisa Lock, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Time to First Composite Heart Failure (HF) Outcome by Treatment and Baseline HF Status and Subtype. Credit: JAMA Internal Medicine (2026). DOI: 10.1001/jamainternmed.2025.7774 An international clinical trial has found that an oral form of semaglutide, a

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Jumping ‘DNA parasites’ linked to early stages of tumor formation

February 27, 2026 / Research update / InnovateMed Author

by Center for Genomic Regulation edited by Sadie Harley, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Part of the sequence of an L1 element as seen on a computer. Credit: Centro de Regulación Genómica A study published in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite, destabilize the cancer genome.

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CRISPR-based platform pinpoints drivers of leukemia in patient cells

February 27, 2026 / Research update / InnovateMed Author / leukemia

by Meagan Raeke, Perelman School of Medicine at the University of Pennsylvania edited by Lisa Lock, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Credit: Molecular Cell (2026). DOI: 10.1016/j.molcel.2026.02.003 A new CRISPR-based tool that is directly used on patients’ cancer cells can identify genes and regulatory elements driving acute myeloid leukemia (AML), an aggressive blood

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At-home gut health tests yield contradictory results, study suggests

February 27, 2026 / Patient education / InnovateMed Author / gut health

by National Institute of Standards and Technology edited by Gaby Clark, reviewed by Robert Egan Editors’ notes The GIST Add as preferred source Diversity Metrics for Genera identified by DTC companies and by NIST. Credit: Communications Biology (2026). DOI: 10.1038/s42003-025-09301-3 Results and health assessments from gut microbiome home-testing kits vary whether they are produced by the same or different manufacturers.

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