August 29, 2025

Q&A: These genetic insights into rheumatoid arthritis could help design better treatments

by Rockefeller University edited by Gaby Clark, reviewed by Andrew Zinin Credit: Unsplash/CC0 Public Domain People with rheumatoid arthritis (RA) often have trouble getting out of bed in the morning, let alone getting to the rheumatologist for a checkup or participating in a research study. This makes a deeper understanding of the mysterious autoimmune disease all the more […]

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Common intracellular toxin could help fight leukemia

by Steve Orbanek, Temple University edited by Gaby Clark, reviewed by Robert Egan   Polθ collaborates with ADH5 and ALDH2 to protect normal and malignant HSPCs against formaldehyde challenge. Credit: Leukemia (2025). DOI: 10.1038/s41375-025-02687-3 All cells naturally produce formaldehyde as a byproduct of metabolism. To survive this toxic stress, both healthy and cancerous blood-forming cells rely on a built-in defense

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Two-stage pimple patches deliver a powerful remedy to unwanted zits

by American Chemical Society edited by Gaby Clark, reviewed by Robert Egan   This new pimple patch features a specialized array of tiny spikes to help deliver acne-busting compounds under the skin.  Credit: ACS Applied Materials & Interfaces (2025). DOI: 10.1021/acsami.5c07718 Waking up with a pimple is no longer a cause for panic, thanks to pimple patches—small, sticker-like bandages that

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Injectable obesity medications associated with reduced risk for eye inflammation

by Cleveland Clinic edited by Gaby Clark, reviewed by Robert Egan Credit: Unsplash/CC0 Public Domain Cleveland Clinic Cole Eye Institute researchers have identified a potential association between the use of GLP-1 receptor agonist (GLP-1RA) therapy and a reduced risk of non-infectious uveitis, a type of eye inflammation. Uveitis is an inflammatory eye condition that affects the uvea, the

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Immune cell therapy for advanced head and neck cancer helps stabilize disease

by University of North Carolina Health Care edited by Stephanie Baum, reviewed by Robert Egan   Credit: Pixabay/CC0 Public Domain A multi-institutional clinical trial conducted at the UNC Lineberger Comprehensive Cancer Center and 21 other U.S. sites found that a single administration of autologous tumor-infiltrating lymphocyte (TIL) cell therapy helped stabilize metastatic head and neck squamous cell carcinoma

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A synthetic molecule helps reduce visceral fat and improve sleep

by Thais Szegö, FAPESP edited by Stephanie Baum, reviewed by Robert Egan   Controlling Pep19 effect in animal model. Credit: Proteimax A study conducted by researchers from the Pennington Biomedical Research Center (PBRC, United States), Proteimax Biotechnology (Israel), and the University of São Paulo’s Biomedical Sciences Institute (ICB-USP, Brazil) has shown that ingesting Pep19 helps reduce visceral fat

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Placebo pain relief works differently across the human body, study finds

by University of Sydney edited by Stephanie Baum, reviewed by Robert Egan   Somatotopic organization of analgesic brainstem circuitry. Placebo analgesia induced on the face, arm, and leg evoked somatotopically organized activity changes within the lateral PAG and RVM revealed through 7-T functional MRI. This analgesic circuitry organization suggests that stimulating discrete brain circuits can produce pain relief

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Dupilumab Treatment Linked to Weight Gain in Patients With Atopic Dermatitis

TOPLINE: Patients with atopic dermatitis (AD) who underwent treatment with dupilumab showed a mean weight gain of 3.6 kg, with 67% of patients experienced an average increase of 5.9 kg. The findings suggested that dupilumab treatment may be associated with weight changes, potentially due to its effect on interleukin-4 signalling and metabolic regulation. METHODOLOGY: Researchers conducted a retrospective chart

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FDA Warns About ‘Mousse’ Sunscreens

The FDA has issued warnings to several manufacturers of “mousse” or “whipped cream” sunscreen products, according to the agency’s website. Over-the-counter sunscreen products are regulated as drugs under the Federal Food, Drug, and Cosmetic Act because they are intended to prevent sunburn and reduce the risk for skin cancer and premature skin aging. However, the

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What is myasthenia gravis and how does it affect sufferers?

by Adam Taylor, The Conversation edited by Robert Egan Credit: CC0 Public Domain Former tennis star Monica Seles has revealed she has been diagnosed with myasthenia gravis, a rare autoimmune condition that affects how the muscles work. The multiple Grand Slam champion says she was actually diagnosed three years ago after experiencing trouble with her vision and weakness in her

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