August 13, 2025

Targeted therapy overcomes cell plasticity in liver cancer mouse models

by The University of Hong Kong edited by Lisa Lock, reviewed by Robert Egan Credit: The University of Hong Kong Researchers from the School of Biomedical Sciences at the LKS Faculty of Medicine, the University of Hong Kong (HKUMed), have made a significant advancement that could reshape the treatment landscape for hepatocellular carcinoma (HCC), the most common type […]

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Blood-based diagnostic biosensor developed to detect PTSD

August 13, 2025 / Research update / InnovateMed Author / PTSD

by University of Tennessee at Knoxville edited by Gaby Clark, reviewed by Alexander Pol Jayne Wu, left, and Shigetoshi Eda work on a biosensor device that detects PTSD. Credit: University of Tennessee Researchers at the University of Tennessee, Knoxville’s Tickle College of Engineering and UT Institute of Agriculture are partnering with technology development firm CFD Research Corporation to

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Two-dose therapy for S. aureus bloodstream infections on par with standard treatment

August 13, 2025 / Research update / InnovateMed Author / Staphylococcus aureus

by National Institutes of Health edited by Sadie Harley, reviewed by Robert Egan Credit: CC0 Public Domain A National Institutes of Health (NIH)-supported clinical trial has found that the outcome of treating complicated Staphylococcus aureus bloodstream infections with two intravenous (IV) doses of the antibiotic dalbavancin seven days apart is just as good as daily IV doses

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New treatment eliminates bladder cancer in 82% of patients

August 13, 2025 / Cancer, Research update / InnovateMed Author / bladder cancer

by University of Southern California edited by Gaby Clark, reviewed by Andrew Zinin TAR-200 is a miniature, pretzel-shaped drug-device duo containing a chemotherapy drug, gemcitabine, which is inserted into the bladder through a catheter and releases the drug for three weeks per treatment cycle. Credit: Johnson & Johnson A new drug-releasing system, TAR-200, eliminated tumors in 82% of

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Naloxone use in older adults: Report covers staying safe with opioids at home

August 13, 2025 / Clinical Practice / InnovateMed Author / naloxone

by The Gerontological Society of America edited by Sadie Harley, reviewed by Robert Egan When patients overdose on a combination of opioids and medetomidine, providing naloxone can help individuals start breathing again but does not reverse the sedation caused by the medetomidine. Credit: Unsplash/CC0 Public Domain With increasing age, older adults are more likely to

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First antidote for carbon monoxide poisoning “cleans” blood in minutes

August 13, 2025 / Research update / InnovateMed Author / antidote, carbonmonoxide

By Bronwyn Thompson August 13, 2025 Invisible killer: Carbon monoxide poisoning accounts for 50,000 emergency room visits each year in the US Depositphotos View 2 Images An engineered protein that acts like a molecular sponge has the potential to change how carbon monoxide poisoning is treated, chasing down CO molecules in the bloodstream and helping the

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New method loads mRNA into exosomes in 10 minutes—just mix and go

August 13, 2025 / Research update / InnovateMed Author / mRNA

KIST team develops cubosome-based method for loading large therapeutics without damaging exosomes Peer-Reviewed Publication National Research Council of Science & Technology image: A visual depiction of the formation process of hybrid exosomes loaded with therapeutic cargo, achieved simply by mixing cubosomes and exosomes. The figure illustrates the actual preparation method, emphasizing the simplicity and ease

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KAIST develops bioelectrosynthesis platform for switch-like precision control of cell signaling

August 13, 2025 / Research update / InnovateMed Author / bioelectrosynthesis

Peer-Reviewed Publication The Korea Advanced Institute of Science and Technology (KAIST image: <(From left)Professor Jimin Park, Ph.D candidate Myeongeun Lee, Ph.D cadidate Jaewoong Lee,Professor Jihan Kim> view moreCredit: KAIST Cells use various signaling molecules to regulate the nervous, immune, and vascular systems. Among these, nitric oxide (NO) and ammonia (NH₃) play important roles, but their chemical instability

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Researchers re-engineer AI language model to target previously ‘undruggable’ disease proteins

August 13, 2025 / Research update / InnovateMed Author / disease protein

McMaster University Hamilton, ON (August 13, 2025) — A study published in Nature Biotechnology reveals a powerful new use for artificial intelligence: designing small, drug-like molecules that can stick to and break down harmful proteins in the body — even when scientists don’t know what those proteins look like. The breakthrough could lead to new treatments for diseases

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Penn developed AI tools and datasets help tailor treatments for kidney patients

August 13, 2025 / Artificial Intelligence, Research update / InnovateMed Author / kidney patient

Penn Medicine and Wharton researchers partner to create CellSpectra and SISKA, offering clues to better treatments for kidney disease and beyond Peer-Reviewed Publication University of Pennsylvania School of Medicine PHILADELPHIA— Doctors treating kidney disease have long depended on trial-and-error to find the best therapies for individual patients. Now, new artificial intelligence (AI) tools developed by

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