This transcript has been edited for clarity. Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I’m Dr F. Perry Wilson from the Yale School of Medicine. The issue I’m discussing this week is bound to be sensitive, so let me try to focus just on the facts. Yes, there are more […]
We Are Seeing More Autism, and It’s Mostly Genetic Read More »
Treatments Prevention Other back pain causes Contacting a doctor Summary Heartburn pain from acid reflux may radiate to the back. Treating back pain may involve lifestyle changes and certain medications. Surgery may also be an option in severe or persistent cases. Acid reflux can cause heartburn, which can cause chest pain. This pain starts in
How to treat back pain caused by acid reflux Read More »
Patients with Parkinson’s disease rarely present to the clinic with the textbook signs — forward stooped posture, slow and rigid movements, or shuffling gait. Instead, the earliest indicators are often vague and nonspecific, though they can later be recognized as early warning signs in retrospect. By the time the first clear symptoms appear, nearly 50%
Forget the Tremor: These Symptoms Come First in Parkinson’s Read More »
While weight loss is often the goal of weight management, weight management in older adults should go beyond weight loss to focus on functional health outcomes, comorbidity improvements, and harm reduction. Beverly Tchang, MD Weight management in older adults requires greater mindfulness and clinical nuance than in younger populations, owing to the increased risk of
Managing Weight in Older Adults Isn’t About Weight at All Read More »
The FDA has approved Widaplik, a triple-drug combination, for the treatment of hypertension in adults. Widaplik combines three drugs — telmisartan, amlodipine, and indapamide — into a single pill that will be available in three doses: 10/1.25/0.625 mg; 20/2.5/1.25 mg, and 40/5/2.5 mg. Intended as initial therapy for patients likely to need multiple medications to
FDA Approves Triple Rx for Hypertension Read More »
European Alliance of Associations for Rheumatology (EULAR) Gout flares are associated with cardiovascular events. Treating gout to target serum urate level prevents flares, but whether such treatment can also prevent cardiovascular events is unknown. An abstract from Edoardo Cipolletta and colleagues explored whether achieving serum urate levels of less than 360 μmol/L within 1 year
New ideas in gout management Read More »
European Alliance of Associations for Rheumatology (EULAR) The first of the selected abstracts came from Wolfgang Merkt, who presented an update on a patient who originally received third-generation CD19-CAR-T cells in 2022. This patient had a rapidly progressive form of systemic sclerosis (SSc) with interstitial lung disease with fatal prognosis. The authors report that CAR-T
Cell-depleting treatment in severe RMD: New data – RMD Read More »
European Alliance of Associations for Rheumatology (EULAR) Axial spondyloarthritis (axSpA) is a chronic inflammatory rheumatic musculoskeletal disease that predominantly affects the axial skeleton.1 axSpA is an umbrella term that comprises the whole spectrum of patients with and without radiographic sacroiliitis, and joint ASAS/EULAR recommendations were published in 2022.2 Radiographic sacroiliitis classifies patients as radiographic axSpA (r-axSpA) and
Risk factors for progression in spondyloarthritis Read More »
by University of Glasgow edited by Sadie Harley, reviewed by Robert Egan Detecting photons through an entire adult head explores the limits of photon transport in the brain, for access to regions of the brain currently inaccessible with noninvasive optical brain imaging. Credit: J. Radford et al., DOI: 10.1117/1.NPh.12.2.025014 For decades, scientists have used near-infrared light to study
by Josep Carreras Leukaemia Research Institute edited by Gaby Clark, reviewed by Robert Egan Overview of the genomic alterations detected by the multi-techniqueapproach. A) G banding and M-FISH of the two karyotypically distinct cellpopulations. B)Circosplot summarizing all the genomic alterations detected by the combination ofdifferent techniques. Rings are as follows (from outer to inner): chromosomecytobands, ROH regions
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